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Researchers
said Sunday they have identified a batch of similar
troubling mutations in coronavirus samples circulating in the
United States. They've not only drawn attention to them; they've come up
with a better shorthand for referring to them. They've named them after
birds using labels such as Robin, Pelican and Bluebird.
The
mutations all affect the same stretch of the spike protein -- the knob-like
extension on the outside of the virus that it uses to dock onto the cells
it infects, the researchers wrote in a pre-print report.
It's not peer reviewed yet, but researchers are rushing such findings
online to share them quickly with other experts.
The
genetic stretch that is mutated, or changed, is called 677. The various
changes are so similar that the researchers think evolution favors these
particular variants. And it's in a troubling place, said Vaughn Cooper,
director of the Center for Evolutionary Biology and Medicine at the
University of Pittsburgh School of Medicine, who worked on the study.
"This
stretch of Spike is important because of its proximity to a region key for
virulence," Cooper told CNN via email.
"We
actually think these mutations are relatively rare (compared to other types
of mutation), but they are disproportionately selected when they
occur," he added.
The
team has been reviewing genomic sequences deposited into GISAID, a global
database that researchers are using to share genetic information about the
virus. It's where scientists first noticed the rise of troubling new variants such
as B.1.1.7, first seen in the United Kingdom, and B.1.351, first seen in
South Africa.
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