Thursday, August 29, 2019

Unhealthy Mix: Obesity and Osteoarthritis

Mingling excess weight and osteoarthritis increases risk for health problems.
By Emily Delzell
The link between being overweight or obese and having osteoarthritis (OA) in weight-bearing joints is fairly easy to understand, though it may be underestimated. Being just 10 pounds overweight puts an extra 30 to 60 pounds of pressure on the knees, for example.
“If you think about all the steps you take in a day, you can see why [being overweight or obese] would lead to premature damage in weight-bearing joints,” says Eric Matteson, MD, chair of the rheumatology division at the Mayo Clinic in Rochester, Minn.
But carrying extra bodyweight in OA does more than create a harmful load on joints. Excess fat also acts in non-mechanical ways to speed the destruction of cartilage and joints, says Peter van der Kraan, PhD, head of experimental rheumatology at Radboud University Medical Center in Nijmegen, the Netherlands. Fat is chemically active and constantly releases inflammation-causing proteins and other biochemicals, such as tumor necrosis factor-α and interleukin-1.
Inflammation and OA
“These proteins travel through your whole body and make it a little inflamed everywhere, including in your joints,” he says. “This constant, low-grade inflammation in your body makes your joints more vulnerable to developing OA, not only in those that are directly loaded by your weight, but also in joints that are not loaded by weight, like the joints in your hands.”
Hand OA is about twice as common among obese people as it is in leaner individuals, he says. Being obese also increases the chances that, once you have OA in a joint or joints, you will develop more OA elsewhere. Obese people with OA in one knee, for example, are five times more likely than healthy-weight people to develop OA in the other knee.
Excess fat tissue not only creates a constant state of low-grade inflammation throughout the body, but, by placing a mechanical load on cartilage and bone, it “activates” those structures, prompting them to release inflammatory protiens and other factors that cause joint destruction, says van der Kraan.
Beyond Joints
Obesity-related damage in OA is not limited to joints. In a 2015 Rheumatology review, van der Kraan detailed the links among obesity, OA and metabolic syndrome. People with OA are almost three times more likely than those in the general population to have metabolic syndrome – a group of conditions, including high blood pressure, high blood sugar, abnormal cholesterol levels, and excess fat around the waist – which is linked to increased risks of heart disease, stroke and diabetes. This association remained strong (though not as high) when the scientists controlled for obesity.
Some researchers, in fact, call the combination of obesity and metabolic syndrome “metabolic OA,” a distinct and dangerous subtype of OA. When these combine, it is a warning sign that should prompt a close look for heart disease, says Francis Berenbaum, MD, head of the department of rheumatology at the Pierre and Maries Curie University in Paris, France, who is studying age-related joint diseases and metabolism.
“When OA is linked to the metabolic syndrome it aggravates cardiovascular diseases linked to metabolism, such as atherosclerosis, probably through an increase in obesity-related inflammation,” he says. “Additionally, the risk for pain, worsening of OA and the need for [total joint replacement surgery] increase with each component of the metabolic syndrome a patient has.”
Fat is Disabling
Being overweight or obese makes the effects of OA more disabling, says John Batsis, MD, associate professor of medicine at the Dartmouth-Hitchcock Medical Center in Lebanon, N.H.
In a 2015 Scandinavian Journal of Rheumatology study, Dr. Batsis and his colleagues analyzed data from the Osteoarthritis Initiative, a study of about 5,000 people with knee OA. Compared with healthy-weight people with OA, they found that people with OA who were obese needed to take more medications, walked more slowly, were much less likely to be physically active and were at significantly higher risk after six years of developing disabilities that interfere with daily life.
“People who were overweight rather than obese had declines compared to those with a normal BMI [body mass index]; however, they were less than those observed in the group with obesity,” he says. “What this tells us is that we should encourage lifestyle modification to patients under the guidance of their clinician so they can safely and effectively lose weight to prevent long-term decline in physical function and risk of disability in the future.”  

https://www.arthritis.org/about-arthritis/types/osteoarthritis/articles/obesity-osteoarthritis.php?utm_source=email&utm_medium=DDM&utm_campaign=OA&mkt_tok=eyJpIjoiWW1NeVl6RXdZV1U1WlRRNCIsInQiOiIwNTJLSktIOVQ3NGx5NW5ZVWFodkExUmQ1aXpBWmdGcEw0Yk13NWo0cE9FWHM5NWtcL3h2d2kzNEJGc2hROXBvZVAxZ0FLSDVvcnJUYnVRbzRnNnFMTmNQamNna2VGOWpGK0ZMY2xcL1dKR0RQSHIxY29WM0lYQzFZSEFNZU5uRnJSIn0%3D

Can I Escape Taxes While Collecting Social Security?

If you go back to work after collecting benefits, can you avoid paying additional Social Security taxes?
Jeff Miller • August 29, 2019
Welcome to “Social Security Q&A.” You ask a Social Security question, our guest expert provides the answer.
You can learn how to ask a question of your own below. And if you would like a personalized report detailing your optimal Social Security claiming strategy, click here.
Check it out: It doesn’t cost much and could result in you receiving thousands of dollars more in benefits over your lifetime.
Today’s question comes from Rose:
“I have been on Social Security for years with no other retirement pension. More than five years ago, I found I had to return to work in order to financially survive at the age of 69. I work for a nonprofit art museum, but Social Security taxes still are being withdrawn.
Will I ever get a raise in my Social Security check while I am able to enjoy it?”
No escape from Uncle Sam
Rose, I am sorry to report that as long as you continue working, you will never escape paying Social Security taxes. As you have observed, you will continue paying Social Security taxes even when you are receiving retirement benefits.
On the other hand, you can expect to receive increases in your retirement benefits. Every year, benefits are increased based on the cost-of-living adjustment (COLA) for the year ending in September.
Some years, retirees see no rise in benefits. For example, because inflation was low at the time, there was no adjustment for 2016. However, there was some good news this year: The increase for 2019 was 2.8%, the largest boost since the one for 2012.
The COLA for 2020 will be announced this fall.
Social Security sends you a statement each year that shows this adjustment. The statement also describes any deductions in your check for items such as Medicare and tax withholding.
Medicare premiums also always go up each year. For 2019, the premium for most people for Medicare Part B (which covers medical services and supplies, while Part A covers hospital services) went up from $134 to $135.50. (High-income retirees pay a higher premium for Medicare.) Tax withholding is optional, but is a good way to set aside money so that you are not hit with a big tax bill when taxes are due.
The reward for working later in life
Since you have returned to work, there is another factor that could increase your benefits: Retirement benefits are based on your highest 35 years of earnings, adjusted for inflation. If your salary now is higher than your earnings in any one of these previous 35 years or you did not previously work for 35 years, your benefits will reflect a recalculation and will be adjusted upward.
If you wish to check on your earnings history, set up an account at My Social Security. In addition to lots of other information, you will find a table there with your earnings history. The numbers in this table have not been adjusted for inflation, so they are not the actual numbers used in the calculation of your benefits.
For example, when calculating a taxpayer’s benefits, Social Security would multiply wages earned in 1980 by 4.02. So if that person earned $8,000 in 1980, his or her wages today would have to exceed $32,160 before today’s wages would replace the wages in 1980 in the benefit calculation.
Multipliers for other years can be found at the Social Security Administration website. Thirty-five years is a pretty long earnings history, so there may well be a year when today’s earnings are greater than a year in the past. That means your Social Security check may well go up — although perhaps only a little — in time for you to enjoy it.
If you have additional questions about your Social Security payout and how it could impact retirement, you might want to consider getting some inexpensive professional help.

https://www.moneytalksnews.com/social-security-qa-can-i-escape-taxes-while-collecting-a-benefit/?utm_campaign=kitchen-gadgets-that-make-healthy-cooking-a-breeze&utm_source=newsletter&utm_medium=email

Long Term Care Reform in Germany – At Long Last

Issue: July 2019 | Long Term Care | English By Sabrina Link
In many countries, how to fund support for old age is a growing issue. At the start of 2017, the German compulsory Long Term Care (LTC) insurance scheme underwent comprehensive reform that reframed the definition of care. Besides introducing a new “in need of care” definition, the reform also added a new evaluation instrument for determining the need for care.
This paper gives background information on the German LTC social security system, presents the new definition and the new care assessment and points out the major changes. It focuses on lessons learned and first experience under the new system, which might be interesting and helpful for other countries. It concludes with the implications this reform has for the private insurance industry with respect to in-force policies, designing of new products and pricing.
Background
LTC insurance, be it public or private, is designed to protect against costs that arise from care needs. It provides cover against the risk of becoming too frail to care for oneself without physical assistance from another person even when using assistive devices.
Demographic and societal changes continue to put pressure on society with respect to elder care. In particular, increasing life expectancy and decreasing fertility rates mean that more people reach a care-relevant age with fewer people to support them. In 1980 life expectancy at age 65 was only 12.8 years for men and 16.3 years for women in Germany (12.6 for men and 16.6 for women in the United Kingdom). In 2015 it was already 17.9 years for men and 21.0 years for women (18.6 for men and 20.8 for women in the United Kingdom) – reflecting an increase of four to six years of life expectancy over a 35-year period.1 In most developed countries, the fertility rate has been below the replacement rate of 2.1 for decades now. It was only 1.5 in Germany (1.8 in the United Kingdom) in 2015 and has been this low since the early 1970s.2 An increased mobility of the younger generations, a higher labour participation by women, and the fact that families are getting smaller and less stable, imply that close relatives who have been the traditional choice in the past are now less likely to take on the role of caregivers.
In countries where a public system exists that encompasses elderly care, these demographic and societal changes exert pressure on the social system since they translate into a smaller share of the population that is of working age. A measure that puts a number on this phenomenon is the old-age dependency ratio. It sets the number of persons aged 65 and over (the age when they are generally economically inactive) in relation to the number of persons aged between 15 and 64 (working age). In the EU-28 countries, this ratio is projected to increase from 0.288 in 2015 to 0.503 in 2050, which indicates that only two persons of working age will be there to support one pensioner.3
The majority of people will need care support during a certain period before death. The experience from a German public health insurer reveals that more than half of all men and almost three out of four women require care at the end of their lives, and that more than 80% of them require it for more than three months.4 Finding solutions to fund the care of the elderly is therefore of key importance in ageing societies.
Germany
Germany is one of the few countries with an established public LTC system and where government and private solutions coexist. In 1995 the public LTC insurance scheme was introduced as the last of the five pillars of social insurance in Germany. Coverage is compulsory, and people are usually insured through their health insurer. The financing of the scheme is based on a pay-as-you-go system. The contribution rate has increased from 1% of gross income at the outset to the current 3.05%, and is shared equally between employee and employer. Those without children pay a surcharge of 0.25 percentage points. The principles of the system are, firstly, the partial nature of the scheme, which bears around half of the actual cost incurred by an individual in need of care. Secondly, home healthcare should take precedence over nursing home care. The benefits are not means-tested and do vary, depending on whether a cash benefit or the reimbursement of care costs is chosen and whether care is provided at home or in a nursing home.
When the compulsory LTC insurance scheme was introduced, it had three care levels. The assessment of the level of care took account of the frequency and duration of the assistance required to provide for personal hygiene, feeding, mobility and housekeeping needs. Other activities, such as measures to promote communication and general care, were explicitly not taken into account. In reaction to the criticism of the focus on physical abilities, a “level 0” was added later. Small levels of benefit were granted to individuals with limited daily living skills, including mainly those with cognitive impairments, such as dementia, but no physical care needs. In addition, the highest care level differentiated so-called hardship cases that manifested extremely high and intensive care needs and surpassed the usual extent in care level III.
The three care levels and hardship cases were defined by the following criteria:
1.     Persons in care level I require assistance for the basic activities (personal hygiene, feeding and mobility) at least once a day and several times a week for housekeeping.
2.     Persons in care level II require assistance for basic activities at least three times a day and several times a week for housekeeping.
3.     Persons in care level III require assistance daily and around the clock for basic activities and several times a week for housekeeping.
The length of time a non-professional spends on average per day caring for the dependent person has to amount to:
·         At least 90 minutes, more than 45 minutes of which are for the basic activities in care level I
·         At least three hours, at least two hours of which are for the basic activities in care level II
·         At least five hours, at least four hours of which are for the basic activities in care level III
Persons in care level III counted as hardship cases if they either needed assistance for the basic activities for at least six hours daily, including at least three times at night, or if the assistance for the basic activities could only be rendered by several care persons together, including at night. Hardship cases were present especially for terminal cancer, terminal AIDS, high paraplegia and tetraplegia, vigil coma and severe manifestation of dementia amongst others.
The reform
From the outset, two features of the care assessment and definition were especially criticized: the insufficient consideration of cognitive aspects and the unsuitable counting of minutes as a criterion to assess the need for care. Over the years, various legal extensions were therefore instituted but never included a thorough reform of the system. Benefits were expanded, “level 0” was introduced (first only for those with a care level, later for all) and a provident fund was established.
Since 2013, a government initiative has promoted private insurance by subsidising (small) premiums, the so-called “Pflege-Bahr”. Nevertheless, a reform was concretely envisaged already in 2006 when an advisory committee to review the care definition was initialised. This committee accomplished much important groundwork, such as outlining a new definition and assessment after thorough research and pre-testing the proposed assessment instrument. Due to changing governments after elections and shifted priorities, further work was delayed, but not abolished. A second committee revised and concretised the new care definition and two larger studies were conducted to validate the new assessment process. Finally, in 2015 the Second Pflegestärkungsgesetz (PSG II) (i.e. the Second Strengthening-of-Care Act) was passed and took effect at the beginning of 2017, more than 10 years after its initialisation. It is embedded within the framework of the First Pflegestärkungsgesetz, which brought an expansion of benefits and the setup of the LTC fund in early 2015, and the Third Pflegestärkungsgesetz, which is to strengthen care counselling in the municipalities from 2017 onward. With the contribution rate increased by 0.2 percentage points, the financing of PSG II was deemed sufficient at the time. However, another increase by 0.5 percentage points from 2019 onward had to be realised.
The new care assessment and definition
The new evaluation instrument for determining the need for care comprises six modules that are weighted differently in the final overall score (Figure 1):
·         Mobility (10%)
·         Cognitive and communicative abilities (higher value from module 2 and 3, in total 15%)
·         Behaviour and psychiatric problems (higher value from module 2 and 3, in total 15%)
·         Self-care (40%)
·         Dealing with requirements due to illness or therapy (20%)
·         Organisation of everyday life and social contacts (15%)
Chart 1
Each module consists of various items. For each item, the assessor records how independently the applicant can perform an activity, if or to what extent an ability is present or how often a certain behaviour occurs. The applicant receives one of the five care grades if the total score is above 12 points of a total of 100 points. For the highest care grade, a special rule applies, and is granted if the applicant has a score of at least 90 points or has lost the use of both arms and both legs.
The assessment philosophy is characterised by five fundamental changes:
·         The allotment of time required for care was replaced by the degree of independence. Heretofore, the evaluation was based on how often and how long the dependent person needed assistance. To that end, the assessor drew on benchmarks as reference points, a complete takeover of the activities by a lay caregiver being assumed. For example, a full-body wash was graded with 20 to 25 minutes. From now on, the extent to which the applicant can shower or bathe independently will be captured.
·         The former deficit orientation is replaced by a resource orientation. It is therefore not a question of what the person in need of care can no longer do, but rather what he or she is still able to do.
·         Previously, the need for care in some activities of daily living was taken into account, consisting of personal hygiene, nutrition, mobility and household assistance. In the future, there will be a comprehensive consideration of the care need. Cognitive and psychiatric impairments will be considered especially in modules 2 and 3 and to some extent in modules 5 and 6. In modules 1 and 4, on the other hand, special emphasis is placed on physical impairments, which continue to be of great relevance due to the high weight of these modules in the total score.
·         The earlier three care levels have been replaced by five care grades. The lowest care grade only serves as a type of preliminary level, though. It has an easy-to-achieve minimum score and relatively low cost reimbursement benefits that can only be used for their specified purpose.
·         In the past, a person had to actually be dependent on assistance for the respective activity. In the future, it will be irrelevant whether the activity in question actually occurs. For example, independence when climbing stairs will be assessed even if there are no stairs in the applicant’s individual living environment.

It is noteworthy that with regard to inpatient care, the contribution to be paid by the person will no longer be dependent on the care grade (except for the lowest care grade). A transition to a higher care grade will therefore not lead to higher contributions, which often led to conflicting interests between nursing home operators and the person in need of care or their relatives. It should be noted, however, that the exact amounts of the deductible and additional costs for investments, board and lodging differ from nursing home to nursing home.
For those who already received benefits from the public LTC insurance system before the reform in 2017, the protection of the status quo is politically intended. Those people are automatically transferred into the new care grades and continue receiving at least the former benefits. A former categorisation into care level x is transferred to care grade x+1. If the dependent person also has limited daily living skills, he or she is transferred to care grade x+2. For example, an individual with care level II before 2017 will be re-categorised into care grade 3. If limited daily living skills were observed in addition to care level II, the person will be categorised into care grade 4.
Implications for private insurance
Additional private LTC insurance policies are available from both the Health and Life insurance line – sometimes with considerable differences. Health insurers offer daily allowances, subsidised LTC insurance policies and the increasingly less important cost reimbursement policies, while life insurers offer annuities. Due to the possibilities to adjust premiums in daily care allowances, the higher guarantee level (including a surrender value) in care annuities and varying interest rates, the price-performance ratios of the policies cannot be compared directly. The initial premium for daily care allowances may appear less expensive when looked at in isolation. This may be one of the most important reasons why the number of in-force policies for health insurers is much higher, amounting to 3.7 million at the end of 2017.5 Even though life insurers managed a portfolio of only 220,000 policies, at the same time they enjoyed a strong growth in recent years.6 Between 2005 and 2017 the number of policies has increased by 24% on average per year, compared to an average annual increase of 13% for Health insurance products.
For LTC insurance policies offered by health insurers, Germany’s PSG II provides for a special adjustment right for conditions and premiums, and even provides a duty to adjust the tariffs in compulsory private LTC insurance and nationally subsidised additional LTC insurance policies. Additional private policies follow the procedure in the compulsory private LTC insurance. For one, this means that the new definition of “in need of care” will be used in new business. It also means benefits offered under existing policies have been adapted based on the new definition of “in need of care”.
Products available from the Life insurance line previously used three definitions – the legal definition of “in need of care”, a definition based on activities of daily living (ADL), and an independent definition of dementia – as benefit triggers. The legal definition was typically copied into the contract wording at a certain point in time with a commentary that changes in the public definition would not lead automatically to changes of the tariff, implying that claims management retained the right to do their own assessment. Because the need for financial support typically increases with the level of dependency, tiered benefits were very popular. This means that the benefit amount depends on the care level or the number of failed ADLs. For example, the insured person receives a partial benefit when failing four out of six ADLs, fulfilling the requirements for care level II or when suffering from dementia and the full benefit in the highest category.
In future claims assessments involving pre-existing policies, two situations are possible: Either those three benefit triggers will have to be taken into consideration, which does not seem impossible since the assessment report based on the new evaluation guidelines will be available; or the insured person will have opted to switch to a new policy, an option that most recent tariffs offer. No new underwriting is required, but the change of tariff must not lead to an extension of the cover, which can lead to a changed (usually lower) benefit than before, due to the more generous nature of the new care definition. Switching to a new tariff can have advantages for the policyholder, even though some specifics, such as the gender-differentiated calculation and higher guaranteed interest rates in earlier product generations, have to be dealt with adequately.
Due to the legal definition, one must ask how a new policy should look. Sticking to the old care levels would do no favour to either the carrier’s public image or its claims management. On the other hand, life insurers have been engaged predominantly with other issues, such as regulatory requirements or the reorientation of private pension products, with the result that only a little capacity is available for revising the LTC product. Thus, there are currently providers that, for the time being, are continuing to use the old care levels or are not using the legal definition at all, favouring the definitions of ADLs and dementia instead.
It is worth considering whether to use the new legal definition exclusively, which covers both physical and psychological disabilities. A separate definition of dementia would then no longer be necessary. On the other hand, a parallel definition of ADLs could at least provide a fallback option in case of future reforms of the public LTC system, even though this might seem unlikely at the moment with the flaws of the old definition appearing to have been corrected. Aside from that, such a parallelism would follow the former market standard. Both variants are currently to be found on the market; some carriers have opted to use only the new social security definition going forward, while others combine it with an ADL definition complemented by a cognitive element to imitate the legal definition.
Tiered benefits still make sense for home healthcare, since the need for financial support continues to be different for each care grade. For nursing home care, this is no longer the case due to the above-mentioned new regulation that the contribution to be paid is no longer dependent on the care grade. However, no one will be able to tell whether potential care will be delivered at home or in a nursing home when taking out LTC insurance. Most products on the market offer an individual fixing of the benefit amount per care grade.
As mentioned above, the lowest care grade (care grade 1) serves as a type of preliminary level with an easy-to-achieve minimum score and relatively low mandatory benefits. The calculation of this care grade involves a number of uncertainties as the assumption regarding the number of additional benefit recipients to expect has a major impact. It therefore seems wise to offer no cover – or only very low cover for care grade 1; for example, in the form of a lump sum benefit. Even a waiver of premiums for reaching care grade 1 could jeopardize the profitability of the tariff because the insurer might not gain enough premiums to pay out later benefits. Therefore, for most products on the market, care annuities can only be paid, and premiums only waived, from care grade 2 upwards.
Differentiating between care grades 4 and 5 is fraught with higher uncertainties than when looking at the other care grades. For the most part, cases with the former care level III can be expected in both care grades. Since further progressed cases with care level III were underrepresented in the studies prior to the reform, differentiating between these two care grades in the calculation is very risky. Furthermore, the average time needed to provide care is nearly the same in care grades 4 and 5. Thus, it is recommended to allow for the same or at least very similar benefit amounts in these care grades. Some products on the market combine the highest two care grades at the outset. Products with fixed levels of benefits offer a high percentage of benefits in care grade 4.
One must also consider whether the assessment of risks in medical underwriting has to change. Dementia-related or mental illnesses affecting behaviour and conditions that involve the patient in the monitoring and/or treatment processes are weighted more heavily than in the past. Fundamental changes in the previous assessments are unnecessary. For example, due to the predictability of care dependency, it was normally impossible to obtain insurance for psychotic schizophrenia, especially when dementia represented an independent benefit trigger.
Another major question is how pricing rates can be derived for the new definition when there has been no actual experience at all. The former relatively robust rates for care levels can be transferred to the new definition using, for one thing, contingency tables of care levels and care grades. These can be obtained from the studies prior to the reform, during which applicants were assessed simultaneously with regard to the former and the new assessment system. Various adjustments might be necessary, like taking into account the effect of “lifting-over-the-threshold”: When assessing claimants with real benefits resulting from it, a gap in the distribution of the scores at the threshold to the next higher care level can be observed. This means that almost no claimant receives a result close to the next higher care level, but clusters receive a score just over it. Scores close to the next higher care level would only lead to objections and, due to the worsening state of health of almost all care recipients, a reassessment only a short time later would confirm the justification of the higher care level. In a study setting, however, this gap cannot be observed, but will probably occur for care grades as well.
Additionally, assumptions about the number of additional benefit recipients are necessary. These are the people that were not care-dependent with regard to the old system, but will be granted a care grade in the new system. One approach is to estimate the number of those who applied but were rejected in the care level system and those who never claimed but are likely to do so in the care grade system. Since the new system has been in place for over two years, first numbers have been published. Public sickness funds, which account for approximately 94% of care recipients, have stated that by the end of 2017 around 304,000 people will have been granted a care grade, but would not have received benefits in the old system.7
Conclusion
The objective of providing more appropriate care grading through the LTC reform appears to have been achieved. In future, people with cognitive and mental health problems will be shown the same recognition for their limitations as people with purely physical impediments. Resource orientation and a focus on the degree of independence replace deficit orientation and the focus on the length of time required for care.
The design of the new care definition and assessment may serve as an inspiration for public LTC schemes elsewhere, be it for schemes to be newly introduced or existing ones to be adjusted. Linking the benefit trigger of a private LTC product to the public definition entails a lot of questions that have to be solved in advance in case of a reform. The challenges for the private insurance industry pointed out above may help private insurers in other countries weigh whether to use the local definition in their products or to use an independent benefit trigger like one based on ADLs. The first has the advantage of a high recognition value for the potential policyholders, but the example of Germany shows that dealing with a reform is a complex and effortful task.
Even though many questions had to be clarified for the practical implementation, some German providers of private LTC insurance have already integrated the new definition of “in need of care” into their products. It remains to be seen how the private insurance market will develop in light of the reform. Insurers will have to maintain a balance between comprehensive insurance cover and payable premiums, as private LTC insurance will remain one of the fastest-growing and future-proof products on the German insurance market, not least due to the demographic trend.

http://www.genre.com/knowledge/publications/ri19-8-en.html?utm_campaign=Subscription%20Management%20Center&utm_source=hs_email&utm_medium=email&utm_content=75147877&_hsenc=p2ANqtz-_yhdl9F8HeTEb6bZGTnx0btCoN2OqjbgKhP0hrmJVWnSs-bOSMHn1EQlXe6rYVIFaAGCZ5nxJwQV2tIk2gt1oWNOs9dA&_hsmi=75147877

Medical Advances and Reality Checks for Underwriters

August 06, 2019 | By Annika Tiedemann 
Earlier this year researchers at Heidelberg University Hospital announced the development of a blood test that can detect breast cancer cells in patients - with higher accuracy than mammography. Around the same time it was reported that a second and third HIV-positive person had been cured of the disease. Then in March 2019 the development of a new Ebola vaccine, created from antibodies taken from a survivor, was announced.
Medical progress happens all the time - with unprecedented speed in the 21st century. New approaches in the fields of prevention, diagnostics and therapy suggest that the extinction of serious diseases could become a reality. In any case, they offer the prospect of earlier discovery or of a more precisely tailored therapy, and they give hope for an improved chance of survival even in the case of hitherto lethal diseases.
But how are these developments reflected in medical underwriting? Does this rapid development mean that underwriting guidelines can be updated frequently to reflect improved outcomes, resulting in more and more cases of standard (medical) risk assessments?
First Priority - A Fundamentally Sound Basis in Medical Research
Underwriting guidelines follow the principle of evidence-based underwriting (EBU). EBU is inspired by (and builds on) the concept of evidence-based medicine (EBM).
EBM has the goal of systematically evaluating the published medical literature and thereby communicating scientifically verified findings. It is important to emphasize that the hierarchical classification by evidence type only reflects the structure of a medical study and says nothing about its content.
The content or the research question of a study can still be of only limited value, even if the study is ranked high according to the grid. The subject-specific evaluation of scientific findings and their consequences for diagnosis, therapy and prognosis requires a great deal of clinical experience and broad coordination. A detailed knowledge of internal and external validity is required to assess whether a clinical trial is “good”.
Big questions have to be answered to evaluate the value and usefulness of a clinical study, including:
·         Is the number of subjects large enough?
·         Is the observation period long enough?
·         How many subjects dropped out?
·         Were the methods suitable and targeted?
From Medical Research to Underwriting - Taking Great Care to Get It Right
EBU developed on the basis of EBM in order to ensure the best possible assessment, i.e., a non-discriminatory offer to the customer, with a risk-adequate premium rate. It does so while taking advantage of the latest valid findings on risk from the clinical field.
Basically, the same types of evidence are used for EBU as in EBM. High demands are placed on the selection of suitable information and the transfer of findings from the clinical context to the context of insurance medicine.
Multiple factors include:
·         The population studied and whether the findings are transferable to the target group of insurance products
·         The reputation of the researcher and the journal the study is published in
·         The main purpose of the research and whether the study design is transferable to the insurance medicine sector
·         The funder of the research and whether the study was conducted with a specific objective that is inconsistent with the objectives of the underwriting guideline
The interpretation of these (and other) factors - as well as the transfer of clinical findings to the insurance context - is the responsibility of relevant experts, most typically medical doctors. Their expertise is also required when it comes to the completion of guidelines in areas where clinical information is not available (e.g., rare diseases, certain age ranges, combinations of diseases, etc.).
Danger of Skipping the Validity Check - Too Quick on the Draw
It’s clear all these steps are important when you look at the reality of medical progress.
·         Only days after the recent announcement of the revolutionary breast cancer blood test by the University of Heidelberg, the school apologized for the premature and misleading marketing of its research results and the hopes that had been prematurely raised.
·         Meanwhile, the apparently cured HIV patients really do exist, but their cure came about in a very specific and not easily replicable way.
·         As for Ebola, things still look grim. Since the summer of 2018 the virus has been raging in the Congo. As of March 2019, more than 1,000 people have been infected and over 600 fatalities confirmed.
Medical progress observed these days (and reflected almost daily in the headlines) is extraordinary. But, for the reasons outlined above, it requires patience for spectacular advances to be reflected in insurance underwriting guidelines that will stand the test of time.

http://www.genre.com/knowledge/blog/medical-advances-and-reality-checks-for-underwriters-en.html?utm_campaign=Subscription%20Management%20Center&utm_source=hs_email&utm_medium=email&utm_content=75385826&_hsenc=p2ANqtz--G_J-qubqsszLZOOMSVJHDZOPNL9IHG0oTa7wqxuXTJt1cbzQB3LfTrTO8eM9SDbtGj4R_li-2rS-QC9sFlhOskCH1RA&_hsmi=75385826

Genetic Testing Put Under the Microscope

August 13, 2019 | By Dr. John O'Brien
Genetic testing is becoming more accessible and commonplace, with new genetic links to diseases regularly being identified. However, the many constraints on the use of predictive genetic tests in insurance means that the easy availability of direct consumer testing is an issue that the industry must consider very carefully.
Genetic science is actually relatively young. Gregor Mendel (1865) is credited with recognizing the transmission of dominant and recessive genes, and towards the end of the 19th century chromosomes were identified in dividing cells under light microscopy.
Messrs Watson and Crick revealed the structure of DNA in 1953 and our understanding of human genetics has progressed rapidly over the last 30 or 40 years. Genetic links to diseases have been recognised for a long time. A good example is haemophilia, which is carried by an X-linked recessive gene and therefore occurs almost exclusively in men.
Genetic tests can be used to give a risk assessment of the development of a disease in the future (predictive tests) or can help confirm an existing condition (diagnostic tests).
Genotyping looks at segments of DNA known as single nucleotide polymorphisms (SNPs). These are variations in sites of DNA identified as being associated with diseases. They are not necessarily causative and are not reliably predictive of the development of a condition.
With the development of next-generation technology, gene sequencing has become quick and relatively affordable. This technique allows the whole genome to be assessed - rather than looking at specific sites associated with previously described diseases.
When assessing the risk of manifestation of a genetic trait, the mode of inheritance is clearly important. For a recessive condition to manifest, the individual must inherit the causative gene from both mother and father. If the condition is dominant, then one gene is sufficient. If the condition is a recessive condition, then the person carrying the gene is very unlikely to manifest the condition.
Understanding these concepts is important in interpreting information that may be provided regarding insurance applicants. The insurance industry is particularly concerned about predictive tests. Very few tests are 100% predictive since even if they do predict the condition, they don’t necessarily predict the degree of penetrance (the proportion of individuals carrying a particular genetic abnormality that will express the clinical symptoms associated with it) or expressivity (which measures the extent to which a given genetic trait is expressed).
A significant development for Life and Health insurers is that over-the-counter genetic tests are becoming increasingly available, and the results go direct to the customer as opposed to being recorded in any medical database. This not only creates the potential for anti-selection, but it also raises a number of concerns regarding the appropriate use of these tests.
From an insurance perspective, the use of genetic information is often limited by legislation or by agreement. In many if not most countries, the use of predictive genetic information to adversely rate an insurance applicant is not permitted. In the UK, there is a moratorium on the use of predictive genetic tests, apart from Huntington’s Disease (for insured amounts over GBP500,000).
It’s important to understand the different types of testing and their implications for underwriters. There are single gene mutations associated with serious illnesses, such as cystic fibrosis, but many conditions, such as ischaemic heart disease, are polygenic in origin. This type of condition in particular is often modified either positively or negatively by behavioural factors such as smoking, diet and exercise. Equally, it is advisable not to ignore a positive family history of disease because there is a negative genetic test.
Over a century ago Queen Victoria was accused of waging biological warfare on the royal houses of Europe after she passed on the haemophilia gene to two of her five daughters, Princess Alice and Princess Beatrice. The mutation was subsequently passed on to the royal families of Spain, Germany and Russia.
So genetics has long been a contentious topic - and no doubt will continue to be so.

http://www.genre.com/knowledge/blog/genetic-testing-put-under-the-microscope-en.html?utm_campaign=Subscription%20Management%20Center&utm_source=hs_email&utm_medium=email&utm_content=75624760&_hsenc=p2ANqtz--pXIz1_BVRcmnWmGj-BnPngPrN-CeSNzsA5KyNf7rntZDZjLgpB4z7O1yMgHqgjxL83fwLb1PZOagaN3hXo5OzxzYJNg&_hsmi=75624760