Is it time to delay second
doses of vaccines? |
Some
experts are arguing that the most effective vaccination strategy is to
double the supply of first doses by having other people delay their
second doses. Experts
are pointing to real world
observations to make their point. Researchers at Israel's largest
hospital saw rates of infection drop 47% among more than 7,000 staff members
in the two weeks following their first doses of the Pfizer-BioNTech vaccine.
The two-dose vaccine regimen is taken 21 days apart. By the second to fourth
week after the first shot, rates of symptomatic infection were down by 85%. In a
second example, Canadian researchers found evidence of more than 90%
protection after a single dose of the Pfizer-BioNTech vaccine. It's
not at all clear how long this protection would last, and both the Pfizer and
Moderna vaccines were tested and authorized on the basis of a two-dose
regimen. The companies, the US Food and Drug Administration, and top
government officials including National Institute of Allergy and Infectious
Diseases Director Dr. Anthony Fauci have cautioned against going outside
what's known and tested. But as
vaccine supply remains limited and more transmissible variants become more
and more common, the race to get as many shots in arms becomes ever more
crucial. |
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