The FDA on Sept. 9 approved Bristol Myers Squibb’s Sotyktu for the treatment of
moderate-to-severe plaque psoriasis in adult patients. It’s a first-in-class
win for the selective allosteric tyrosine kinase 2 (TYK2) inhibitor. BMS
acquired Sotyktu as part of its 2019 merger with Celgene Corporation, with
Amgen purchasing Celgene’s extant immunology drug Otezla in order for
regulators to approve the deal. But now Otezla may be in trouble with Sotyktu
on the market, as the TYK2 inhibitor proved more affective than Otezla in
clinical trials. For the treatment of psoriasis, 98% of all insured lives
have covered or better access to Otezla under the pharmacy benefit. 8.6% of
lives have preferred access to Otezla, growing to 54.3% with utilization
management restrictions applied. |
SOURCE: MMIT Analytics,
as of 9/14/22 |
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